Xiaoyuan Song, PhD
EDUCATION AND RESEARCH EXPERIENCE
2012.12-present Professor, Youth Thousand Talents Program, University of Science & Technology of China,
2006-2012 Postdoctoral fellow, University of California, at San Diego, CA, USA
1999-2006 Ph.D, University of Rochester, USA
1996-1999 M.S, Beijing Normal University, China
1992-1996 B.A, Biology, Beijing Normal University, China
RESEARCH INTERESTS
1. Roles of three-dimensional transcriptional regulation of lncRNA and genome structure in brain aging
2. Transcriptional regulation of lncRNA and chromatin interaction in spermatogenesis
3. Function and molecular mechanism of meiosis specific genes
REPRESENTATIVE PUBLICATIONS
1. Muhammad A, Waheed R, Khan NA, Jiang H, Song X, piRDisease v1.0: a manually curated database for piRNA associated diseases. Database (Oxford). 2019 Jan 1;2019. pii: baz052.
2. Wang F, Ren D, Liang X, Ke S, Zhang B, Hu B, Song X, Wang X, A long noncoding RNA cluster-based genomic locus maintains proper development and visual function. Nucleic Acids Res. 2019 Jul 9;47(12):6315-6329
3. Mamun MA, Mannoor K, Cao J, Qadri F, Song X, SOX2 in Cancer Stemness: Tumor Malignancy and Therapeutic Potentials. J Mol Cell Biol. 2018 Dec 5.
4. Xu Q, Wang R, Ghanam AR, Yan G, Miao W, Song X, The key role of CYC2 during meiosis in Tetrahymena thermophila. Protein Cell. 2016 Apr;7(4):236-249.
5. Lü M., Tian H., Cao Y., He X., Chen L., Song X., Ping P., Huang H., Sun F. Downregulation of miR-320a/383-sponge-like long non-coding RNA NLC1-C (narcolepsy candidate-region 1 genes) is associated with male infertility and promotes testicular embryonal carcinoma cell proliferation. Cell Death Dis. 2015, doi: 10.1038/cddis.
6. Li W., Hu Y., Oh S., Ma Q., Merkurjev D., Song X., Zhou X., Liu Z., Tanasa B., He X., Chen AY., Ohgi K., Zhang J., Liu W., Rosenfeld MG. Condensin I and II Complexes License Full Estrogen Receptor α-Dependent Enhancer Activation.Mol Cell. 2015, 59(2):188-202.
7. Cao J., Luo Z., Cheng Q., Xu Q., Zhang Y., Wang F., Wu Y., Song X.*. Three-dimensional regulation of transcription. Protein & Cell. 2015, 6(4):241-53.
8. Zhang F., Tanasaa B. #, Merkurjev D. #, Lin C. #, Song X., Li W, Tan Y, Liu Z., Zhang J., Ohgi KA., Kronesa A., Skowronska-Krawczyka D., Rosenfeld MG. Enhancer-bound LDB1 regulates a corticotrope promoter-pausing repression program. PNAS. 2015, 112(5):1380-5.
9. Wang X.* and Song X.*, Glass C.K., and Rosenfeld M.R. The long arm of long non-coding RNAs: Roles as sensors regulating gene transcriptional programs. Cold Spring Harb Perspect Biol. 2011 doi: 10.1101/cshperspect.a003756. *Equal contributors.A chapter in《The RNA World》, 4th edition.
E-mail: songxy@ustc.tsg211.com
Phone: 0551-63607752