Kai Zhong, PhD
EDUCATION AND RESEARCH EXPERIENCE
2000-2002 Research associate, Medical Department, Brookhaven National Lab
2005-2007 Post-doc, Freiburg University
2007-2009 Deputy of department chair, Dept. Biomedical MR at Otto-von-Guericke University Magdeburg
2010-present Professor, High Magnetic Field Laboratory, Chinese Academic of Science
RESEARCH INTERESTS
1.High Field Magnetic Resonance Imaging Techniques and Related Applications.
The development of novel MRI methods at high field is essential to reveal subcortical brain structures and its functions. The advantage of improved image resolution at 9.4 T can play a significant role in this endeavor. Other modalities, such as opto-fMRI, and tissue transparency techniques, could be combined with MRI to provide novel information of the brain structure and connectivity.
2.Brain Structural and Functional Magnetic Resonance Imaging of None Human Primate Animals.
The brain development and neuronal degeneration is a major clinical focus. Primate research at 9.4 T has unique advantage, given the closer similarities to human being, that could potentially provide more insight into the progression and degeneration of neuronal diseases.
REPRESENTATIVE PUBLICATIONS
1. Cao Y, Xu H, Zhu Y, Shi MJ, Wei L, Zhang J, Cheng S, Shi Y, Tong H, Kang L, Lu L, Luo H, Yang X, Bai X, Wang R, Ma Y, Wang Y, Wang Z, Zhong K, Zhao BQ, Fan W, ADAMTS13 maintains cerebrovascular integrity to ameliorate Alzheimer-like pathology. PLoS Biol. 2019 Jun 11;17(6):e3000313
2. Xiao J, Zhang G, Xu R, Chen H, Wang H, Tian G, Wang B, Yang C, Bai G, Zhang Z, Yang H, Zhong K, Zou D, Wu Z, A pH-responsive platform combining chemodynamic therapy with limotherapy for simultaneous bioimaging and synergistic cancer therapy. Biomaterials. 2019 Sep;216:119254
3. Hai Z, Ni Y, Saimi D, Yang H, Tong H, Zhong K, Liang G, γ-Glutamyltranspeptidase-Triggered Intracellular Gadolinium Nanoparticle Formation Enhances the T2-Weighted MR Contrast of Tumor. Nano Lett. 2019 Apr 10;19(4):2428-2433.
4. Dong L, Qian J, Hai Z, Xu J, Du W, Zhong K, Liang G, Alkaline Phosphatase-Instructed Self-Assembly of Gadolinium Nanofibers for Enhanced T2-Weighted Magnetic Resonance Imaging of Tumor. Anal Chem. 2017 Jul 5;89(13):6922-6925
5. Yuan Y, Ding Z, Qian J, zhang J,Xu J, Dong X, Han T, Ge S, Luo Y, Wang Y, ZhongK, Liang G.
Casp3/7-InstructedIntracellular Aggregation of Fe3O4 Nanoparticles Enhances T2 MR Imaging ofTumor Apoptosis. Nano Lett. 2016 Apr 13;16(4):2686-91
6. Zhong, K., et al., Phase contrast imaging in neonates. Neuroimage,2011. 55(3): p. 1068-1072.2.
7. Zhong, K., et al., Themolecular basis for gray and white mattercontrast in phase imaging. Neuroimage, 2008. 40(4): p.1561-1566.3.
8. Zhong, K., et al., Systematic investigation of balanced steady-statefree precession for functional MRI in the human visual cortex at 3 tesla. MagneticResonance in Medicine, 2007. 57(1): p. 67-73.4.
5.6 Hennig, J., K. Zhong, and O. Speck,MR-Encephalography: Fast multi-channel monitoring of brain physiology withmagnetic resonance. Neuroimage, 2007. 34(1): p. 212-219.
Website：http://english.hmfl.cas.cn/about_us/professors/201208/t20120831_90467.html
E-mail: kzhong@hmfl.ac.cn
Phone：0551-63601736